Justin Bieber's "Love Yourself" was an international commercial success, reaching number one on the Canadian Hot 100, the Billboard Hot 100 (where it became Bieber's third consecutive number-one in both countries), and the UK Singles Chart. "Love Yourself" also topped the charts in Australia, Denmark, Ireland, the Netherlands, New Zealand, and Sweden.

"Love Yourself" was first released as a promotional single after the release of Purpose, it was later announced as the album's official third radio single. In the United States, the song debuted at number four on the Billboard Hot 100, giving Bieber his ninth top ten song and his third consecutive top ten debut from Purpose. It also debuted at number two and four on the Digital Songs and Streaming Songs charts, respectively, with 141,000 downloads and 17.4 million streams. The following week, it descended to number seven on the Hot 100. Two weeks later, it ascended from seven to five on the Hot 100, meanwhile Bieber's "Sorry" and "What Do You Mean?" were at number two and four, respectively. Thus, when "Love Yourself" debuted at number four, Bieber had three concurrent songs in the Hot 100's top five, becoming the third act to achieve it since 50 Cent in 2005. Bieber and the The Beatles are the only acts to earn the honor as a lead artist on all three songs. On the chart dated 6 February 2016, "Love Yourself" ascended from three to two on the Hot 100, meanwhile Bieber's "Sorry" was at number one. With that, Justin Bieber became the 17th act in the Hot 100's history to rank at Nos. 1 and 2 simultaneously. He was the 11th act to hold the Hot 100's top two as a lead artist on both songs. The following week, "Love Yourself" replaced "Sorry" at number one, becoming his third consecutive number-one single. Thus, Bieber was the 12th artist to succeed himself in the Hot 100's 57-year history; the last artist before Bieber was The Weeknd, who is also from Canada. Additionally, Bieber's Purpose became the first album by a male artist to produce three number-one songs since Justin Timberlake's FutureSex/LoveSounds did so in 2006/2007.[16] After being replaced at the top of the Hot 100 by Zayn Malik's debut single as a solo artist "Pillowtalk" for one week, it returned to the number one position the following date. Also, "Love Yourself" replaced "Sorry" at the top of the Radio Songs chart with 144 million weekly audience, becoming Bieber's second number-one song on the chart. However, the next week, "Love Yourself" was replaced at the top by Rihanna's "Work" and descended to number two. The song has sold 1.5 million copies in the U.S. and is still the best-selling Song of the First Quarter of 2016!

In the United Kingdom, "Love Yourself" debuted at number three on the UK Singles Chart on 19 November 2015, after the release of Purpose. The following week, it rose to number two before replacing "Sorry" at the top of the chart on 4 December 2015. Bieber is the first artist to replace themselves at the chart's summit since Elvis Presley in 2005. "Love Yourself" marked Bieber's third consecutive chart-topping song in Britain. The following week, the song stayed at the top of the chart with 114,000 combined sales and "Sorry" stayed at number two, which made Bieber the first artist ever to knock himself off the top spot with both songs holding at 1 and 2 for two consecutive weeks. "Love Yourself" and "Sorry" remained at the same place the next week, which made Bieber the first artist ever to log four weeks at Numbers 1 and 2 consecutively, breaking the record previously held by The Beatles, who logged three consecutive weeks at Numbers 1 and 2 in 1967/68. "Love Yourself" was beaten to the top by NHS Choir's "A Bridge Over You" charity single by nearly 31,000 chart sales. However, the single rose to the number-one spot the next week, logging a fourth week at the summit and claiming the first number-one song of 2016. The following week, it remained at number one, making Bieber the first artist on the UK Singles Chart to occupy the top three spots on the chart at the same time with "Sorry" at number two and "What Do You Mean?" climbing one place to three. "Love Yourself" spent six non-consecutive weeks at number one. On 4 January 2016, the Official Charts Company announced that 'Love Yourself' had earned 719,000 combined sales.

In Australia, "Love Yourself" debuted at number three on the ARIA Singles Chart, after the release of Purpose, giving Bieber his fifth top-three single in the country. That week the singer had three songs inside the top ten: "Sorry", "Love Yourself" and "What Do You Mean?". Two weeks later, "Love Yourself" was the most streamed track in the country and rose to number two, also it earned a gold certification for sales of over 35,000 copies. In its fourth week, the song ascended from two to one, dethroning Adele's "Hello" and earning a platinum certification for sales of over 70,000 copies. With that, Bieber became the only act to have two number-one songs in 2015 following previous single "What Do You Mean?", which topped the chart during four consecutive weeks in September. The song stayed at the top of the chart the following two weeks. On its third week at number one, Bieber's 'Sorry' and "What Do You Mean?" were at number two and eight, respectively. With that, Bieber became the first act to dominate the top two positions since Macklemore did in 2013 with "Same Love" and "Thrift Shop". He also was the first act to have three singles inside the chart's top ten since 2012. The song is No.8 on the list for the most accumulated weeks at number one in the 2010s. Also, it is his longest running No.1 single in Australia. "Love Yourself" also topped the charts in Sweden, Ireland, New Zealand, The Netherlands and Denmark.

"love Yourself" was first number-one song of 2016 and has spent seven consecutive weeks at number one, which places Bieber at No.1 in the first Quarter chart of 2016!